LSM6 Antibody

Cusabio

LSM6 Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

LSM6

LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

YDR378C, U6 snRNA-associated Sm-like protein LSm6, LSM6 U6 small nuclear RNA and mRNA degradation associated, LSM6 homolog, U6 small nuclear RNA associated, Sm protein F

Rabbit

IgG

U6 snRNA-associated Sm-like protein LSm6

Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5-to-3 mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).

Human

-20°C or -80°C

41116161