LT052

MedChem Express

LT052 [2543545-44-2]

10

2543545-44-2

Research Use Only

98.77

C22H19N5O4S

449.48

LT052 is a highly selective BET BD1 inhibitor with an IC 50 of 87.7 nM. LT052 exhibits nanomolar BRD4 BD1 potency and 138-fold selectivity over BRD4 BD2 (IC 50 =12.130 microM). LT052 has anti-inflammatory?activity and can be used for acute gout arthritis research [1] .

O=S(C1=CC=CC=C1OC)(NC2=C3N=C(N4C=C(C)N=C4)C=C5C3=C(N(C)C5=O)C=C2)=O

-20°C,2°C to 8°C

12352200