LU-005i [1620107-33-6]

MedChem Express

LU-005i [1620107-33-6]

14

1620107-33-6

Research Use Only

98.24

C31H46N4O7

586.72

LU-005i is a potent inhibitor of beta5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over beta5c subunit (IC50 = 287 nM)[1].

COC(C=C1)=CC=C1C[C@H](NC([C@H](C)NC(CN2CCOCC2)=O)=O)C(N[C@@H](CC3CCCCC3)C([C@]4(CO4)C)=O)=O

-20°C

12131703