Luminespib (NVP-AUY922)
S1069
CAS Number747412-49-3
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameLuminespib (NVP-AUY922) [747412-49-3]
- Delivery Days Customer9
- CAS Number747412-49-3
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionLuminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90alpha/beta with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rbeta protein and results in growth inhibition, autophagy and apoptosis. Phase 2.
- Storage Instruction-80°C
- UNSPSC51202000
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Product group Chemicals
CAS Number747412-49-3
Estimated Purity≥99%
Molecular Weight465.5 Da
- SizePrice
