Lurosetron

MedChem Express

Lurosetron

5

Research Use Only

C17H17FN4O

312.34

Lurosetron (GR-87442) is a 6-fluoro analogue of Alosetron (HY-70050A). Lurosetron is a serotonin 5-HT3 receptor antagonist. Lurosetron inhibits recombinant (rbt) CYP1A2, with an IC50 of 0.1 microM. Lurosetron also inhibits other CYP isoforms, including rbtCYP2C9 and rbtCYP3A4 with IC50s ranging between 3.5 microM and 16 microM.[1].

O=C1C2=C(CCN1CC3=C(NC=N3)C)N(C)C4=C2C=CC=C4F

12352200