LUT014
HY-111940
CAS Number2274819-46-2
Product group Chemicals
Estimated Purity97.23
Molecular Weight528.49
Overview
- SupplierMedChem Express
- Product NameLUT014 [2274819-46-2]
- Delivery Days Customer5
- CAS Number2274819-46-2
- CertificationResearch Use Only
- Estimated Purity97.23
- Molecular FormulaC27H19F3N8O
- Molecular Weight528.49
- Scientific DescriptionLUT014 is a topical inhibitor targeting BRAF that cannot pass through the blood-brain barrier. LUT014 inhibits BRAF kinase and abnormally activates the MAPK/ERK signaling pathway, promoting the proliferation of epidermal keratinocytes, repairing skin barrier damage caused by radiation damage, and alleviating inflammatory responses. LUT014 is independent of RAS signaling and accelerates the repair and regeneration of damaged skin cells. LUT014 can be used to study radiation dermatitis, especially skin damage caused by breast cancer radiotherapy[1][2][3].
- SMILESFC(F)(F)OC1=CC(NC2=NC=CC3=C2C=CC(C)=C3NC4=NC=CC=C4C5=C6N=CNC6=NC=N5)=CC=C1
- Storage Instruction2°C to 8°C
- UNSPSC12352200
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Product group Chemicals
LUT014 [2274819-46-2]T15794
CAS Number2274819-46-2
Estimated Purity0.9634
Molecular Weight528.49
- SizePrice
Product group Chemicals
LUT014ORB1308108
CAS Number2274819-46-2
Estimated Purity99.03%
Molecular Weight528.49
- SizePrice