Luzindole

MedChem Express

Luzindole [117946-91-5]

5

117946-91-5

99.62

C19H20N2O

292.37

Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel 1b ) over MT1 (Mel 1a ) with K i values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity [1] [2] [3] .

CC(NCCC1=C(CC2=CC=CC=C2)NC3=C1C=CC=C3)=O

-20°C

12352200