LXQ46

MedChem Express

LXQ46

5

Research Use Only

C23H17Br2NO5

547.19

LXQ46 is an orally active inhibitor for protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 0.190 microM. LXQ46 enhances insulin and leptin signaling pathways in insulin-resistant C2C12. LXQ46 ameliorates type 2 diabetes and increases insulin tolerance in mouse models[1].

BrC1=C(O)C(O)=CC(C2=NC=C(C3=CC=C(OC4=CC=C(C=C4)OCC)C=C3)O2)=C1Br

12352200