LY-195448 (hydrochloride) [111112-18-6]

MedChem Express

LY-195448 (hydrochloride) [111112-18-6]

9

111112-18-6

Research Use Only

C20H27ClN2O2

362.89

LY-195448 hydrochloride is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models. LY-195448 hydrochloride acts by blocking cells at metaphase. LY-195448 hydrochloride has demonstrated a lack of standard side effects commonly associated with cancer treatments, such as myelosuppression and gastrointestinal toxicity. LY-195448 hydrochloride was evaluated in a phase I trial, where it showed only mild and reversible side effects like hypotension, tachycardia, and tremor.

NC(C(C=C1)=CC=C1CCC(C)(C)NC[C@@H](C2=CC=CC=C2)O)=O.Cl

12352200