LY 2389575 hydrochloride

Biorbyt

LY 2389575 hydrochloride

10

885104-09-6

Research Use Only

100.00%

C15H16BrCl3N4

438.58

LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of beta-amyloid (Abeta), and can be used to study Alzheimers disease. It can be used to study Alzheimers disease.

N(CC1=C(Cl)C=C(Cl)C=C1)[C@@H]2CN(CC2)C=3N=CC(Br)=CN3.Cl

-20°C

12352200