Bio-Connect

LY-2624587

HY-P991656
MedChem Express
Product group Antibodies
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Overview

  • Supplier
    MedChem Express
  • Product Name
    LY-2624587
  • Delivery Days Customer
    999
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Scientific Description
    LY-2624587 is a humanized IgG4 monoclonal antibody antagonist targeting CXCR4. LY-2624587 blocks SDF-1/CXCR4 interaction and SDF-1-induced GTP binding. LY-2624587 significantly inhibits cell migration and induces apoptosis in human lymphoma and leukemia cells. LY-2624587 also inhibits CXCR4 and SDF-1 mediated cell signaling including activation of MAPK and AKT. LY-2624587 can be used for human hematological malignancies like acute myeloid leukemia (AML) research[1][2].
  • UNSPSC
    41116161