Bio-Connect

LY-294,002 [154447-36-6] [154447-36-6]

BS-75397C
Bioss
CAS Number154447-36-6
Product group Chemicals
Estimated Purity>99%
Molecular Weight307.4
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Overview

  • Supplier
    Bioss
  • Product Name
    LY-294,002 [154447-36-6] [154447-36-6]
  • Delivery Days Customer
    16
  • CAS Number
    154447-36-6
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Estimated Purity
    >99%
  • Molecular Formula
    C19H17NO3
  • Molecular Weight
    307.4
  • Scientific Description
    Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.
  • SMILES
    O=C1C=C(OC2=C(C=CC=C12)C1=CC=CC=C1)N1CCOCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12161509