LY 379196

MedChem Express

LY 379196

9

Research Use Only

C30H34N4O5S

562.68

LY 379196 is a PKC-beta inhibitor (IC50: 50 nM and 30 nM for PKC betaI and betaII respectively). LY 379196 inhibits the VEGF, IGF-1 and bFGF-induced proliferation of bovine retinal microvascular endothelial cells (BREC). LY 379196 is an antiproliferatory agentfor proliferative retinopathy[1][2].

O=C1NC(C2=C1C(C3=CC=CC=C34)=CN4CCC[C@H](CN(C)C)CCN5C6=CC=CC=C6C2=C5)=O.O=S(O)(C)=O

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