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LY2857785 [1619903-54-6]

LY2857785 [1619903-54-6]

TQ0060
TargetMol Chemicals
CAS Number1619903-54-6
Product group Chemicals
Estimated Purity96%
Molecular Weight448.6
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    LY2857785 [1619903-54-6]
  • Delivery Days Customer
    9
  • CAS Number
    1619903-54-6
  • Certification
    Research Use Only
  • Chemical Name
    LY2857785
  • Estimated Purity
    96%
  • Molecular Formula
    C26H36N6O
  • Molecular Weight
    448.6
  • Scientific Description
    LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)c1n(C)nc2ccc(cc12)-c1ccnc(N[C@H]2CC[C@@H](CC2)NC2CCOCC2)n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Yin T, Lallena MJ, Kreklau EL, et al. A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models. Mol Cancer Ther. 2014,13(6):1442-56. doi: 10.1158/1535-7163.MCT-13-0849
    Read this paper

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