LY294002 [154447-36-6]
HY-10108
CAS Number154447-36-6
Product group Chemicals
Estimated Purity99.95
Molecular Weight307.34
Overview
- SupplierMedChem Express
- Product NameLY294002 [154447-36-6]
- Delivery Days Customer5
- CAS Number154447-36-6
- CertificationResearch Use Only
- Estimated Purity99.95
- Molecular FormulaC19H17NO3
- Molecular Weight307.34
- Scientific DescriptionLY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 microM for PI3Kalpha, PI3Kdelta and PI3Kbeta, respectively[1]. LY294002 also inhibits CK2 with an IC50 of 98 nM[2]. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 microM. LY294002 is an apoptosis activator[3].
- SMILESO=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12131703
MSDS
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