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LY294002

HY-10108
MedChem Express
CAS Number154447-36-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.95
Molecular Weight307.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    LY294002 [154447-36-6]
  • Delivery Days Customer
    5
  • CAS Number
    154447-36-6
  • Estimated Purity
    99.95
  • Molecular Formula
    C19H17NO3
  • Molecular Weight
    307.34
  • Scientific Description
    LY294002 is a broad-spectrum inhibitor of PI3K with IC 50 s of 0.5, 0.57, and 0.97 microM for PI3Kalpha , PI3Kdelta and PI3Kbeta , respectively [1] . LY294002 also inhibits CK2 with an IC 50 of 98 nM [2] . LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC 50 of 1.4?microM. LY294002 is an apoptosis activator [3] .
  • SMILES
    O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200