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ProductsBack/LY3295668 [1919888-06-4]

LY3295668 [1919888-06-4]

HY-114258
MedChem Express
CAS Number1919888-06-4
Product group Chemicals
Estimated Purity99.76
Molecular Weight489.95
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Overview

  • Supplier
    MedChem Express
  • Product Name
    LY3295668 [1919888-06-4]
  • Delivery Days Customer
    10
  • CAS Number
    1919888-06-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.76
  • Molecular Formula
    C24H26ClF2N5O2
  • Molecular Weight
    489.95
  • Scientific Description
    LY3295668 (AK-01) is a highly specific and orally active inhibitor of Aurora-A kinase with a Ki values for AurA and AurB of 0.8 nM and 1038 nM respectively. LY3295668 can effectively inhibit the autophosphorylation of AurA, induce mitotic arrest and apoptosis. LY3295668 avoids the formation of polyploids related to AurB inhibition. LY3295668 can be used for the study of small cell lung cancer[1][2].
  • SMILES
    O=C([C@@]1(CC2=NC(NC3=NNC(C)=C3)=CC=C2F)C[C@@H](C)N(CC4=CC=CC(Cl)=C4F)CC1)O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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LY3295668 [1919888-06-4]
Product group Chemicals
References
TargetMol Chemicals
LY3295668 [1919888-06-4]T15815
CAS Number1919888-06-4
Estimated Purity≥98%
Molecular Weight489.95
  • SizePrice