LY487379 (hydrochloride) [353229-59-1]
HY-103552
CAS Number353229-59-1
Product group Chemicals
Molecular Weight488.91
Overview
- SupplierMedChem Express
- Product NameLY487379 (hydrochloride) [353229-59-1]
- Delivery Days Customer10
- CAS Number353229-59-1
- CertificationResearch Use Only
- Molecular FormulaC21H20ClF3N2O4S
- Molecular Weight488.91
- Scientific DescriptionLY487379 hydrochloride is a selective human mGluR2 positive allosteric modulator (PAM). LY487379 hydrochloride potentiates glutamate-stimulated [35S]GTPgammaS binding with EC50 values of 1.7 microM and >10 microM for mGlu2 and mGlu3 receptors respectively. LY487379 hydrochloride promotes cognitive flexibility and facilitates behavioral inhibition in a rat model. LY487379 hydrochloride can be used for schizophrenia research[2].
- SMILESFC(F)(F)CS(=O)(N(C1=CC=C(OC2=CC=CC=C2OC)C=C1)CC3=CC=CN=C3)=O.[H]Cl
- UNSPSC12352200
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