LYP-IN-1

MedChem Express

LYP-IN-1 [1404436-51-6]

10

1404436-51-6

Research Use Only

99.78

C28H20ClNO6

501.91

LYP-IN-1 is a potent, selective and specific LYP inhibitor with a K i and an IC 50 of 110 nM and 0.259 microM, respectively. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 ( IC 50 =5 microM) and SHP2 ( IC 50 =2.5 microM). LYP-IN-1 exhibits highly efficacious cellular activity in T- and mast cells. LYP-IN-1 can be used for the study of autoimmune disorders [1] . LYP-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(C1=C(O)C=C(OC(C2=CC=C(OCC(NC3CC3)=O)C=C2)=C4C#CC5=CC=CC(Cl)=C5)C4=C1)O

-20°C,2°C to 8°C

12352200