LZTR2 antibody

GeneTex

LZTR2 antibody

9

WB: 1 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SEC16B

SEC16 homolog B, endoplasmic reticulum export factor

leucine zipper transcription regulator 2; LZTR2; PGPR-p117; protein SEC16 homolog B; protein transport protein Sec16B; regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein; RGPR; RGPR-p117; SEC16S

Rabbit

IgG

Protein transport protein Sec16B

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203