LZTS1 antibody [C1C3]
GTX117376
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLZTS1
Overview
- SupplierGeneTex
- Product NameLZTS1 antibody [C1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.61 mg/ml
- ConjugateUnconjugated
- Gene ID11178
- Target nameLZTS1
- Target descriptionleucine zipper tumor suppressor 1
- Target synonymsF37; F37/Esophageal cancer-related gene-coding leucine-zipper motif; FEZ1; leucine zipper putative tumor suppressor 1; leucine zipper, putative tumor suppressor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y250
- Protein NameLeucine zipper putative tumor suppressor 1
- Scientific DescriptionThis gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer. Lovat F et al., 2014 Feb 28, OncotargetRead more