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ProductsBack/m-Chlorophenylbiguanide [48144-44-1]

m-Chlorophenylbiguanide [48144-44-1]

HY-121299
MedChem Express
CAS Number48144-44-1
Product group Chemicals
Estimated Purity90.0
Molecular Weight211.65
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Overview

  • Supplier
    MedChem Express
  • Product Name
    m-Chlorophenylbiguanide [48144-44-1]
  • Delivery Days Customer
    9
  • CAS Number
    48144-44-1
  • Certification
    Research Use Only
  • Estimated Purity
    90.0
  • Molecular Formula
    C8H10ClN5
  • Molecular Weight
    211.65
  • Scientific Description
    m-Chlorophenylbiguanide (mCPBG) is a potent high-affinity agonist of the 5-HT3 receptor, exhibiting an inhibitory effect on long-term potentiation (LTP) in the mossy fiber-CA3 system. mCPBG attenuates the magnitude of LTP at concentrations of 0.3-1 microM, demonstrating its role in modulating synaptic plasticity. Additionally, the impact of mCPBG on LTP is reversible by the GABAA receptor antagonist bicuculline, indicating a connection between its action and GABAergic neurotransmission.
  • SMILES
    N=C(NC1=CC=CC(Cl)=C1)NC(N)=N
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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