M24 [2761947-05-9]

MedChem Express

M24 [2761947-05-9]

10

2761947-05-9

Research Use Only

C44H40Cl3N5O11S

953.24

M24 is a Mcl-1 selective inhibitor. M24 exhibits good binding affinity against Mcl-1 with Ki value of 0.33 microM. M24 exhibits good anti-proliferative activity and induce apoptosis in HepG2 cells[1].

CC1=CC(OCCOC2=CC=C(C=C2)CN3CC(N(C3=O)CC(NC(C(NS(=O)(C4=CC([N+]([O-])=O)=C(C=C4)Cl)=O)=O)CC5=CC=C(C=C5)OCC6=CC=C(C=C6)Cl)=O)=O)=CC(C)=C1Cl

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