m7(3Ma-Cy7)Gppp(2OMe)ApG ammonium

MedChem Express

m7(3Ma-Cy7)Gppp(2OMe)ApG ammonium

5

Research Use Only

C68H86N18O30P4S2.xNH3

1823.54 (free base)

m7(3Ma-Cy7)Gppp(2OMe)ApG ammonium is a Cy7-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Cy7 by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.

CC(/C(N1CCCCCC(NC[C@H]2[C@@H](O)[C@H](N(C=[N+]3C)C4=C3C(NC(N)=N4)=O)O[C@@H]2COP(OP(OP(OC[C@H]5O[C@@H](N(C=N6)C7=C6C(N)=NC=N7)[C@H](OC)[C@@H]5OP(OC[C@H]8O[C@@H](N(C=N9)C%10=C9C(NC(N)=N%10)=O)[C@H](O)[C@@H]8O)(O)=O)(O)=O)(O)=O)(O)=O)=O)=C\C=C\C=C\C=C\C%11=[N+](CC)C(C=CC(S(=O)([O-])=O)=C%12)=C%12C%11(C)C)(C)C%13=C1C=CC(S(=O)([O-])=O)=C%13.N.[x]

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