m7GpppAmpG [62858-30-4]

MedChem Express

m7GpppAmpG [62858-30-4]

10

62858-30-4

Research Use Only

C32H43N15O24P4+

1145.66

m7GpppAmpG (m7G(5)ppp(5)(2OMeA)pG) is a trinucleotide 5 end cap analog. m7GpppAmpG binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG caps RNA with a capping efficiency of 90%. m7GpppAmpG enhances mRNA stability and translation efficiency. m7GpppAmpG is used in mRNA therapeutic research[1][2][3].

O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](OC)[C@H](N5C=NC6=C(N)N=CN=C65)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O])=O)(O)=O

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