(- ) -Maackiain [2035-15-6]

MedChem Express

(- ) -Maackiain [2035-15-6]

10

2035-15-6

Research Use Only

99.91

C16H12O5

284.267

(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-kappaB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active[1][2].

OC1=CC=C([C@@]2([H])[C@@](C3=C(C=C4C(OCO4)=C3)O2)([H])CO5)C5=C1

2°C to 8°C

12352200