Macro H2A.2 antibody [N3C3]

GeneTex

Macro H2A.2 antibody [N3C3]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MACROH2A2

macroH2A.2 histone

core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2AFY2; histone macroH2A2; mH2A2

Rabbit

IgG

Core histone macro-H2A.2

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203