(+)-Macrosphelide A [172923-77-2]

TargetMol Chemicals

(+)-Macrosphelide A [172923-77-2]

16

172923-77-2

Chemical

Research Use Only

(+)-Macrosphelide A

C16H22O8

342.344

(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+)-Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 microg/ml, respectively), but not Gram-negative bacteria or fungi.

3 years

C[C@H]1CC(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O1 - t:10,19 -

-20°C

12352200