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ProductsBack/Macrosporin [22225-67-8]
Chemical Structure
Chemical Structure
Chemical Structure

Macrosporin [22225-67-8]

Research Use Only
AG-CN2-0497
AdipoGen Life Sciences
CAS Number22225-67-8
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight284.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Macrosporin
  • Delivery Days Customer
    10
  • CAS Number
    22225-67-8
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C16H12O5
  • Molecular Weight
    284.3
  • Scientific Description
    Anthraquinone antibiotic. Moderate antibacterial agent. Photosensitizer (through ROS production) and leaf necrosis inducer. Antiproliferative. Moderate cytotoxic in selected cancer cells. Shown to inhibit several protein kinases, including Aurora B and FLT3 in low microM range. Mycotoxin. Useful as a reference in food analysis. - Chemical. CAS: 22225-67-8. Formula: C16H12O5. MW: 284.3. Isolated from Stemphylium sp. Anthraquinone antibiotic. Moderate antibacterial agent. Photosensitizer (through ROS production) and leaf necrosis inducer. Antiproliferative. Moderate cytotoxic in selected cancer cells. Shown to inhibit several protein kinases, including Aurora B and FLT3 in low microM range. Mycotoxin. Useful as a reference in food analysis.
  • SMILES
    OC1=CC2=C(C(C(C=C(OC)C=C3O)=C3C2=O)=O)C=C1C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Studies on the metabolic products of Macrosporium porri Elliott Part IV. Structure of Macrosporin (Group III): R. Suemitsu, et al.; Agr. Biol. Chem. 25, 100 (1961)
  • Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium: U. Hoeller, et al.; J. Nat. Prod. 65, 876 (2002)
  • Bioactive metabolites from the endophytic fungus Stemphylium globuliferum isolated from Mentha pulegium: A. Debbab, et al.; J. Nat. Prod. 72, 626 (2009)
  • Protein kinase inhibitors and other cytotoxic metabolites from the fungal endophyte Stemphylium botryosum isolated from Chenopodium album: A.H. Aly, et al.; Mycosphere - J. Fungal Biol. 1, 153 (2010)
  • The role of macrosporin in necrotic spots: A. Trigos, et al.; Phytochem. Lett. 4, 122 (2011)
  • Bioactive hydroanthraquinones and anthraquinone dimers from a soft coral-derived Alternaria sp. Fungus: C.-J. Zheng, et al.; J. Nat. Prod. 75, 189 (2012)