MAD2L1BP antibody

GeneTex

MAD2L1BP antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

MAD2L1BP

MAD2L1 binding protein

caught by MAD2 protein; CMT2; MAD2L1-binding protein; p31(comet)

Chicken

IgY

MAD2L1-binding protein

May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Human

-20°C or -80°C,2°C to 8°C

12352203