MAF1 antibody
GTX106776
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMAF1
Overview
- SupplierGeneTex
- Product NameMAF1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID84232
- Target nameMAF1
- Target descriptionMAF1 negative regulator of RNA polymerase III
- Target synonymsrepressor of RNA polymerase III transcription MAF1 homolog, MAF1 homolog, negative regulator of RNA polymerase III, homolog of yeast MAF1
- HostRabbit
- IsotypeIgG
- Protein IDQ9H063
- Protein NameRepressor of RNA polymerase III transcription MAF1 homolog
- Scientific DescriptionThis gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Li Y, Xiao D, Chen H, et al. Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023,26(12):108544. doi: 10.1016/j.isci.2023.108544Read this paper
- Lee HK, Lee BR, Lee TJ, et al. Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys. Sci Rep. 2022,12(1):1646. doi: 10.1038/s41598-022-05648-3Read this paper
- Lee YL, Li YC, Su CH, et al. MAF1 represses CDKN1A through a Pol III-dependent mechanism. Elife. 2015,4:e06283. doi: 10.7554/eLife.06283Read this paper



