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MAF1 antibody

GTX106776
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMAF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    MAF1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID84232
  • Target name
    MAF1
  • Target description
    MAF1 homolog, negative regulator of RNA polymerase III
  • Target synonyms
    homolog of yeast MAF1; MAF1 negative regulator of RNA polymerase III; repressor of RNA polymerase III transcription MAF1 homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9H063
  • Protein Name
    Repressor of RNA polymerase III transcription MAF1 homolog
  • Scientific Description
    This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms.
    Read more
  • Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys. Lee HK et al., 2022 Jan 31, Sci Rep
    Read more
  • MAF1 represses CDKN1A through a Pol III-dependent mechanism. Lee YL et al., 2015 Jun 12, Elife
    Read more

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Figure 1. Western blotting validation for Anti-MAF1 Antibody A03332 Western blot (WB) analysis of MAF1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:RAW264.7 whole cell lysate Lane3:H9C2 whole cell lysate Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
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