MAF1 antibody
GTX106776
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMAF1
Overview
- SupplierGeneTex
- Product NameMAF1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID84232
- Target nameMAF1
- Target descriptionMAF1 homolog, negative regulator of RNA polymerase III
- Target synonymshomolog of yeast MAF1; MAF1 negative regulator of RNA polymerase III; repressor of RNA polymerase III transcription MAF1 homolog
- HostRabbit
- IsotypeIgG
- Protein IDQ9H063
- Protein NameRepressor of RNA polymerase III transcription MAF1 homolog
- Scientific DescriptionThis gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms.Read more
- Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys. Lee HK et al., 2022 Jan 31, Sci RepRead more
- MAF1 represses CDKN1A through a Pol III-dependent mechanism. Lee YL et al., 2015 Jun 12, ElifeRead more