Mafosfamide sodium [84211-05-2]

TargetMol Chemicals

Mafosfamide sodium [84211-05-2]

72

84211-05-2

Research Use Only

Mafosfamide sodium

C9H18Cl2N2NaO5PS2

423.24

Mafosfamide sodium is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide sodium alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, Mafosfamide sodium, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, Mafosfamide sodium is potentially useful in the intrathecal treatment of neoplastic meningitis.

3 years

[Na+].[O-]S(=O)(=O)CCS[C@@H]1CCOP(=O)(N1)N(CCCl)CCCl

-20°C

12352200