MAGI1 antibody

GeneTex

MAGI1 antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

MAGI1

membrane associated guanylate kinase, WW and PDZ domain containing 1

AIP3; AIP-3; atrophin-1-interacting protein 3; BAI1-associated protein 1; BAIAP1; BAP1; BAP-1; MAGI-1; MAGI-1b; Magi1d; membrane-associated guanylate kinase inverted 1; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; TNRC19; trinucleotide repeat-containing gene 19 protein; WW domain-containing protein 3; WWP3

Rabbit

IgG

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

The MAGUK (Membrane-Associated Guanylate Kinase) family of proteins is characterized by the presence of multi-PDZ and SH3 domains, and a single region of homology to Saccharomyces cerevisiae guanylate kinase (GuK) domain. All MAGUKs studied to date localize to regions of cell-cell contact such as tight junctions in epithelial cells and synaptic junctions in neurons and are believed to be involved in the assembly of multi-protein complexes via their protein-protein interaction domains. Three novel, closely related MAGUK proteins were isolated by means of different screening assays, and named MAGI1/BAP1, MAGI2/ S-SCAM /ARIP, and SLIPR/MAGI3. MAGI1 was first identified in mouse as a protein interacting with K-RasB. Three isoforms were identified, and named MAGI1a, MAGI1b, and MAGI1c, of 1139, 1171, and 1374 amino acids respectively. The isolation of a growing number of MAGI1 binding partners, together with the determination of the subcellular and tissue distribution of the different isoforms, are paving the way towards elucidation of its function.

Rat

-20°C or -80°C,2°C to 8°C

12352203