MAGL-IN-4

MedChem Express

MAGL-IN-4 [2135785-20-3]

5

2135785-20-3

Research Use Only

99.91

C18H21ClN2O4

364.82

MAGL-IN-4 is an orally active, selective and reversible monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 6.2 nM. MAGL-IN-4 can penetrate the blood-brain barrier (BBB). MAGL-IN-4 enhances endocannabinoid signaling mostly by the increase in the level of 2-AG via selective MAGL inhibition in the brain[1].

CC1=C(C=C(C=C1)COC2CN(C([C@H]3C[C@]4(COC(N4)=O)C3)=O)C2)Cl

-20°C,2°C to 8°C

12352200