Mal-C6-alpha-Amanitin [1578249-76-9]

MedChem Express

Mal-C6-alpha-Amanitin [1578249-76-9]

10

1578249-76-9

Research Use Only

99.14

C55H78N12O17S

1211.34

Mal-C6-alpha-Amanitin is a agent-linker conjugate for ADC with potent antitumor activity by using alpha-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.

O=S1C2=C(C[C@]3([H])NC([C@](NC([C@@]4([H])N(C[C@H](O)C4)C([C@@](CC(N)=O)([H])NC([C@](NC(CNC([C@@]([C@@H](C)CC)([H])NC(CNC3=O)=O)=O)=O)([H])C1)=O)=O)=O)([H])[C@@H](C)[C@@H](O)CO)=O)C5=CC=C(OCCCCCCNC(CCCCCN6C(C=CC6=O)=O)=O)C=C5N2

-20°C

41115800