Mal-PEG4-VC-PAB-DMEA-PNU-159682 [2259318-52-8]

MedChem Express

Mal-PEG4-VC-PAB-DMEA-PNU-159682 [2259318-52-8]

10

2259318-52-8

Research Use Only

96.17

C74H98N10O27

1559.62

Mal-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].

C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCN(C)C(OCC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN7C(C=CC7=O)=O)=O)=O)=O)=O)C=C6)=O)=O)=O)(O)C4)C(O)=C8C(C(C9=C(OC)C=CC=C9C8=O)=O)=C5O

-20°C

41115800