Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682

MedChem Express

Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682

5

Research Use Only

C67H81N7O27

1416.39

Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682 is an active molecule-conjugate for ADCs, composed of a cleavable Val-Ala linker and the potent ADC cytotoxic payload PNU-159682 (HY-16700)[1].

OC1=C2C(C(C(C(OC)=CC=C3)=C3C2=O)=O)=C(O)C4=C1C[C@](C(COC(N(C)CCN(C)C(OCC5=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CN6C(C=CC6=O)=O)=O)=O)=O)C=C5CC[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O7)=O)=O)=O)(O)C[C@@H]4O[C@H]8C[C@H](N(CCO[C@@H]9OC)[C@@H]9O%10)[C@H]%10[C@H](C)O8

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