Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-beta-Glu-PAB
HY-173635
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameMal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-beta-Glu-PAB
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC63H98N6O31
- Molecular Weight1435.47
- Scientific DescriptionMal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-beta-Glu-PAB is an interchain cysteines to a Maleimide-reactive, beta-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639)[1].
- SMILESO=C(O)OCC1=CC=C(O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)C(CNC(CCNC([C@@H](NC(CCN3C(C=CC3=O)=O)=O)CCCC(N[C@@H]4[C@@H](OC[C@@H]5NC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)[C@@H]5OC4)=O)=O)=O)=C1
- UNSPSC41115800