Maleimido-tri(ethylene glycol)-propionic acid [518044-40-1]
HY-130426
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameMaleimido-tri(ethylene glycol)-propionic acid [518044-40-1]
- Delivery Days Customer9
- CAS Number518044-40-1
- CertificationResearch Use Only
- Estimated Purity99.14
- Molecular FormulaC13H19NO7
- Molecular Weight301.29
- Scientific DescriptionMaleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1]. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- SMILESO=C(O)CCOCCOCCOCCN1C(C=CC1=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41115800