Malotilate

MedChem Express

Malotilate [59937-28-9]

10

59937-28-9

Research Use Only

99.47

C12H16O4S2

288.38

Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC50=4.7 microM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes[1][2].

O=C(OC(C)C)/C(C(OC(C)C)=O)=C1SC=CS\1

-20°C,2°C to 8°C

12352200