MAN1B1, Human (HEK293, His)

MedChem Express

MAN1B1, Human (HEK293, His)

10

Research Use Only

98.0

MAN1B1

mannosidase alpha class 1B member 1

ERMAN1, ERManI, MANA-ER, MRT15, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ER alpha 1,2-mannosidase, Man9GlcNAc2-specific processing alpha-mannosidase, endoplasmic Reticulum Class I alpha-mannosidase, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

MAN1B1, integral to glycoprotein quality control, trims a single alpha-1,2-linked mannose from Man(9)GlcNAc(2), producing Man(8)GlcNAc(2). In the ERQC, elevated enzyme concentrations allow further trimming to Man(5-6)GlcNAc(2). This enzymatic function is crucial for glycoprotein processing and quality control in the endoplasmic reticulum, ensuring proper folding and maturation. MAN1B1 Protein, Human (HEK293, His) is the recombinant human-derived MAN1B1 protein, expressed by HEK293 , with C-6*His labeled tag.

-80°C

41116100

Human