Manassantin B [88497-88-5]

TargetMol Chemicals

Manassantin B [88497-88-5]

9

Research Use Only

C41H48O11

716.81

Manassantin B is a potent inhibitor of NF-IB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-IB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.

C[C@H]1[C@](O[C@@]([C@@H]1C)(C2=CC(OC)=C(O[C@@H]([C@H](O)C=3C=C4C(=CC3)OCO4)C)C=C2)[H])(C5=CC(OC)=C(O[C@@H]([C@H](O)C6=CC(OC)=C(OC)C=C6)C)C=C5)[H]

-20°C

12352200