WB analysis of 293T cells using GTX45981 MANEA antibody at 0.2-1microg/ml.
WB analysis of 293T cells using GTX45981 MANEA antibody at 0.2-1microg/ml.
MANEA antibody, Internal
GTX45981
Overview
- SupplierGeneTex
- Product NameMANEA antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID79694
- Target nameMANEA
- Target descriptionmannosidase endo-alpha
- Target synonymsalpha 1,2-endomannosidase; ENDO; endo-alpha mannosidase; endomannosidase; glycoprotein endo-alpha-1,2-mannosidase; hEndo; mandaselin
- HostRabbit
- IsotypeIgG
- Protein IDQ5SRI9
- Protein NameGlycoprotein endo-alpha-1,2-mannosidase
- Scientific DescriptionN-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203