Manzamine A [104196-68-1]
HY-117025
CAS Number104196-68-1
Product group Chemicals
Estimated Purity98.2
Molecular Weight548.76
Overview
- SupplierMedChem Express
- Product NameManzamine A [104196-68-1]
- Delivery Days Customer10
- CAS Number104196-68-1
- CertificationResearch Use Only
- Estimated Purity98.2
- Molecular FormulaC36H44N4O
- Molecular Weight548.76
- Scientific DescriptionManzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3beta and CDK-5 with IC50s of 10.2 microM and 1.5 microM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1[1][2][3][4].
- SMILESO[C@]1(CC/C=C\CCCC2)[C@@]3([H])[C@@](C[C@@]4([H])N3CCCC/C=C\4)(C[N@@]2CC5)[C@]5([H])C(C6=C(NC7=CC=CC=C87)C8=CC=N6)=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![Manzamine A [104196-68-1]](https://www.targetmol.com/group3/M00/02/C0/CgoaEGY7PN2EYuocAAAAAJ1eY0E140.png)