MAO-B-IN-10

MedChem Express

MAO-B-IN-10 [2376710-36-8]

10

Research Use Only

C23H26N2O4

394.46

MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetrated MAO-B (monoamine oxidase-B) inhibitor, with IC50 of 5.3 microM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Abeta (amyloid beta) aggregation. MAO-B-IN-10 can be use for Alzheimers disease research[1].

CCN(C(OC1=C(C=C(C=C1)/C=C/C(N2CCC3=C(C2)C=CC=C3)=O)OC)=O)C

12131703