The data was published in the journal J Biomed Sci in 2018. PMID: 29499695
The data was published in the journal J Biomed Sci in 2018. PMID: 29499695
MAP3K1 antibody, C-term
GTX46204
Overview
- SupplierGeneTex
- Product NameMAP3K1 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4214
- Target nameMAP3K1
- Target descriptionmitogen-activated protein kinase kinase kinase 1
- Target synonymsMAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MAPKKK1; MEK kinase 1; MEKK; MEKK 1; MEKK1; mitogen-activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; SRXY6
- HostRabbit
- IsotypeIgG
- Protein IDQ13233
- Protein NameMitogen-activated protein kinase kinase kinase 1
- Scientific DescriptionThe protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts. Lin CH et al., 2018 Mar 2, J Biomed SciRead more