MAP3K12 Polyclonal Antibody

Reddot Biotech

MAP3K12 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

MAP3K12

mitogen-activated protein kinase kinase kinase 12

DLK; dual leucine zipper bearing kinase; dual leucine zipper kinase DLK; leucine zipper protein kinase; MAPK-upstream kinase; MEKK12; mitogen-activated protein kinase kinase kinase 12; mixed lineage kinase; MUK; protein kinase MUK; ZPK; ZPKP1

Rabbit

IgG

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

Human, Mouse, Rat

-20°C

12352203