MAP3K9 Antibody, Biotin conjugated

Cusabio

MAP3K9 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

MAP3K9

mitogen-activated protein kinase kinase kinase 9

MEKK9; mitogen-activated protein kinase kinase kinase 9; mixed lineage kinase 1 (tyr and ser/thr specificity); MLK1; PRKE1

Rabbit

IgG

Mitogen-activated protein kinase kinase kinase 9

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Human

-20°C or -80°C

12352203