Western Blot Positive WB detected in: Rat lung tissue All lanes: MAP3K9 antibody at 2.7ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 122, 124 kDa Observed band size: 122 kDa
MAP3K9 Antibody
CSB-PA013434LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMAP3K9
Overview
- SupplierCusabio
- Product NameMAP3K9 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4293
- Target nameMAP3K9
- Target descriptionmitogen-activated protein kinase kinase kinase 9
- Target synonymsMEKK9; mitogen-activated protein kinase kinase kinase 9; mixed lineage kinase 1 (tyr and ser/thr specificity); MLK1; PRKE1
- HostRabbit
- IsotypeIgG
- Protein IDP80192
- Protein NameMitogen-activated protein kinase kinase kinase 9
- Scientific DescriptionSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203