WB analysis of truncated Trx-MAP4K4 recombinant protein (1), MBP-MAP4K4 (aa300-400) recombinant protein (2) and MAP4K4(aa194-436)-hIgGFc transfected CH0-K1 cell lysate(3) using GTX83190 MAP4K4 antibody [4H9E7].
WB analysis of truncated Trx-MAP4K4 recombinant protein (1), MBP-MAP4K4 (aa300-400) recombinant protein (2) and MAP4K4(aa194-436)-hIgGFc transfected CH0-K1 cell lysate(3) using GTX83190 MAP4K4 antibody [4H9E7].
MAP4K4 antibody [4H9E7]
GTX83190
Overview
- SupplierGeneTex
- Product NameMAP4K4 antibody [4H9E7]
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4H9E7
- ConjugateUnconjugated
- Gene ID9448
- Target nameMAP4K4
- Target descriptionmitogen-activated protein kinase kinase kinase kinase 4
- Target synonymsepididymis secretory protein Li 31; FLH21957; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK4; mitogen-activated protein kinase kinase kinase kinase 4; nck-interacting kinase; NIK; Ste20 group protein kinase HGK
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203