Bio-Connect

MAP855 [1660107-77-6]

HY-145702
MedChem Express
CAS Number1660107-77-6
Product group Chemicals
Estimated Purity98.48
Molecular Weight564.97
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MAP855 [1660107-77-6]
  • Delivery Days Customer
    10
  • CAS Number
    1660107-77-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.48
  • Molecular Formula
    C28H23ClF2N6O3
  • Molecular Weight
    564.97
  • Scientific Description
    MAP855 is a highly potent, selective, ATP-competitive and orally active MEK1/2 kinase inhibitor (MEK1 ERK2 cascade IC50=3 nM, pERK EC50=5 nM). MAP855 shows equipotent inhibition of wild-type and mutant MEK1/2[1].
  • SMILES
    CC1=NC2=C(C3=CC(C4=C(C=C(C=C4)OC5=NC=CC=N5)Cl)=C(F)C=C3N=C2)N1[C@]6([H])[C@H](CN(CC6)C(CO)=O)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200